Sprix Spray

Pronunciation: KEE-toe-ROLE-ak
Generic Name: Ketorolac
Brand Name: Sprix

Sprix Spray is only intended for short-term (up to 5 days) treatment of moderate to moderately severe pain. It should not be used to treat minor or long-term pain. Do not use more of Sprix Spray than prescribed. Do not use Sprix Spray to treat children.

Sprix Spray is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious, and sometimes fatal, heart and blood vessel problems (eg, a heart attack, a stroke). The risk may be greater if you already have heart problems or if you take Sprix Spray for a long time. Do not use Sprix Spray right before or after coronary artery bypass graft (CABG) surgery.

Sprix Spray may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.

Do not use Sprix Spray if:

• you are allergic to Sprix Spray, aspirin, or any other NSAIDs (eg, ibuprofen, celecoxib)


• you are taking another NSAID (eg, ibuprofen, celecoxib)


• you are in the last 3 months of pregnancy, are breast-feeding, or are in labor


• you have recently had or will be having CABG surgery


• you have a stomach ulcer or a history of ulcers or certain severe stomach or bowel problems (eg, bleeding, perforation)


• you have severe kidney problems or are at risk of kidney failure (eg, low blood volume, dehydrated)


• you have bleeding in the brain (eg, a stroke, an aneurysm) or bleeding problems (eg, platelet disorder, hemophilia), or you are at risk of bleeding

Do not use Sprix Spray to prevent pain before any major surgery.

Sprix Spray is used for:

The short-term (up to 5 days) treatment of moderate to moderately severe pain.

Sprix Spray is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes these symptoms.

Do NOT use Sprix Spray if:

• you are allergic to any ingredient in Sprix Spray


• you have had an asthma attack, hives, or another severe allergic reaction (eg, severe rash, breathing difficulties, dizziness) to aspirin, or to an NSAID (eg, ibuprofen, naproxen, celecoxib)


• you have had a severe allergic reaction to ethylenediamine tetraacetic acid (EDTA)


• you are in the last 3 months of pregnancy, are breast-feeding, or are in labor


• you have recently had or will be having coronary artery bypass graft (CABG) surgery


• you have a stomach ulcer, or a history of ulcers or certain severe stomach problems (eg, bleeding, perforation)


• you have severe kidney problems or are at risk of kidney failure (eg, low blood volume, dehydrated)


• you have bleeding in the brain (eg, a stroke, an aneurysm), bleeding or clotting problems (eg, a platelet disorder, hemophilia), or you are at risk of bleeding


• you need to prevent pain before any major surgery


• you are taking pentoxifylline, probenecid, another formulation of Sprix Spray (eg, tablets, injection), or another NSAID (eg, ibuprofen, celecoxib)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sprix Spray:

Some medical conditions may interact with Sprix Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of kidney or liver problems, diabetes, stomach or bowel problems (eg, bleeding, perforation, ulcers, ulcerative colitis, Crohn disease), or frequent heartburn


• if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation


• if you have high blood pressure, blood disorders (eg, anemia, porphyria), bleeding or clotting problems, heart problems (eg, heart failure), blood vessel disease, or you are at risk of any of these diseases


• if you have poor health, dehydration or low fluid volume, low blood sodium levels, smoke, drink alcohol, or have a history of alcohol abuse


• if you take corticosteroids (eg, prednisone) or anticoagulants (eg, warfarin)


• if you weigh less than 110 lbs (50 kg)


• if you have recently taken other formulations of Sprix Spray (eg, tablets, injection)

Some MEDICINES MAY INTERACT with Sprix Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin and other blood thinners (eg, dalteparin), pentoxifylline, rivaroxaban, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), thienopyridines (eg, clopidogrel), or other NSAIDs (eg, ibuprofen, celecoxib) because the risk of bleeding may be increased


• Probenecid because it may increase the risk of Sprix Spray's side effects


• Alprazolam, cyclosporine, lithium, methotrexate, quinolones (eg, ciprofloxacin), or thiothixene because the risk of their side effects may be increased by Sprix Spray


• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), carbamazepine, diuretics (eg, furosemide, hydrochlorothiazide), or phenytoin because their effectiveness may be decreased by Sprix Spray

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sprix Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Sprix Spray:

Use Sprix Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Sprix Spray comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Sprix Spray refilled.


• Before you use each bottle for the first time, you must prime it. Remove the clear plastic cover and the blue plastic safety clip. Hold the bottle at arm's length away from you. Using your index and middle fingers on the top of the bottle and your thumb on the bottom of the bottle, press down evenly and release the pump 5 times. The bottle is now ready to use.


• To use this nose spray, gently blow your nose. Sit up straight or stand and tilt your head forward slightly. Place the tip of the spray container into the nose. Be sure to point the container away from the center of your nose. Breathe gently through the nostril and squeeze the spray container. If your dose requires 2 sprays, repeat the process for your other nostril. Replace the clear plastic cover after each use.


• Do NOT use Sprix Spray for more than 5 days. Sprix Spray is not for the treatment of mild to moderate or chronic pain (eg, headache).


• Avoid contact with the eyes. If you get Sprix Spray in your eyes, rinse it out with water. If eye irritation persists for more than 1 hour, contact your doctor.


• Each bottle contains 1 day's supply of Sprix Spray. Discard each bottle within 24 hours of opening it, even if it still contains some unused medicine.


• If you miss a dose of Sprix Spray and you are taking it regularly, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sprix Spray.

Important safety information:

• Sprix Spray may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Sprix Spray with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Serious stomach ulcers or bleeding can occur with the use of Sprix Spray. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Sprix Spray with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.


• Do NOT take more than the recommended dose, use more often than prescribed, or use for longer than prescribed without checking with your doctor.


• Tell your doctor or dentist that you take Sprix Spray before you receive any medical or dental care, emergency care, or surgery.


• If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.


• Sprix Spray is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (eg, ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do not take aspirin while you are using Sprix Spray unless your doctor tells you to.


• Check with your doctor or pharmacist before you take acetaminophen while you are taking Sprix Spray. The risk of liver problems may be increased.


• Lab tests, including kidney or liver function, blood electrolyte levels, complete blood cell counts, or blood pressure, may be performed while you use Sprix Spray. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Sprix Spray with caution in the ELDERLY; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.


• Sprix Spray should not be used in CHILDREN younger than 17 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Sprix Spray may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sprix Spray while you are pregnant. Sprix Spray is found in breast milk. Do not breast-feed while taking Sprix Spray.

Possible side effects of Sprix Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; increased tearing; mild nasal discomfort, irritation, or pain; mild stomach pain or upset; nausea; throat irritation; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue, unusual hoarseness); bloody or black, tarry stools; bloody or cloudy urine; change in the amount of urine produced or trouble urinating; chest, jaw, or left arm pain; confusion; dark urine; depression; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; loss of appetite; mental or mood changes; mouth sores; numbness of an arm or leg; one-sided weakness; pale stools; persistent flu-like symptoms; red, swollen, blistered, or peeling skin with or without fever; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting or diarrhea; shortness of breath; sudden or unexplained weight gain; swelling of the arms, hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Sprix side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased urination; loss of consciousness; seizures; severe dizziness or drowsiness; severe nausea, vomiting, or stomach pain; slow or troubled breathing; tremor; unusual bleeding or bruising; vomit that looks like coffee grounds.

Proper storage of Sprix Spray:

Store unopened bottles of Sprix Spray in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store opened bottles of Sprix Spray at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store upright, away from heat, moisture, and light. Discard opened bottles of Sprix Spray within 24 hours of opening. Do not store in the bathroom. Keep Sprix Spray out of the reach of children and away from pets.

General information:

• If you have any questions about Sprix Spray, please talk with your doctor, pharmacist, or other health care provider.


• Sprix Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Sprix Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Sprix resources

• Sprix Side Effects (in more detail)
• Sprix Use in Pregnancy & Breastfeeding
• Sprix Drug Interactions
• Sprix Support Group
• 8 Reviews for Sprix - Add your own review/rating

Compare Sprix with other medications

• Pain

Tricodene SF Liquid

Pronunciation: klor-fen-IHR-ah-meen/DEX-troe-meth-OR-fan
Generic Name: Chlorpheniramine/Dextromethorphan
Brand Name: Examples include Scot-Tussin DM and Tricodene SF

Tricodene SF Liquid is used for:

Relieving cough and other symptoms, such as runny nose and sneezing, due to colds, upper respiratory infections, or allergies. It may also be used for other conditions as determined by your doctor.

Tricodene SF Liquid is an antihistamine and cough suppressant combination. It works by blocking histamine, which reduces allergy symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Tricodene SF Liquid if:

• you are allergic to any ingredient in Tricodene SF Liquid


• you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tricodene SF Liquid:

Some medical conditions may interact with Tricodene SF Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of asthma; lung problems (eg, emphysema); adrenal gland problems (eg, tumor); heart problems; high blood pressure; diabetes, heart blood vessel problems; stroke, glaucoma; a blockage of your stomach, intestines, or bladder; ulcers; trouble urinating; an enlarged prostate; seizures; or an overactive thyroid

Some MEDICINES MAY INTERACT with Tricodene SF Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Furazolidone, MAO inhibitors (eg, phenelzine), or sodium oxybate (GHB) because the risk of serious side effects, such as severe low blood pressure, severe drowsiness, breathing problems, fever, severe muscle problems, and possibly death, may be increased by Tricodene SF Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tricodene SF Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tricodene SF Liquid:

Use Tricodene SF Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tricodene SF Liquid may be taken with or without food.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Tricodene SF Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tricodene SF Liquid.

Important safety information:

• Tricodene SF Liquid may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tricodene SF Liquid. Using Tricodene SF Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Do NOT exceed the recommended dose or take Tricodene SF Liquid for longer than prescribed without checking with your doctor.


• If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.


• Tricodene SF Liquid may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Tricodene SF Liquid. Use a sunscreen or protective clothing if you must be outside for a prolonged period.


• If you are scheduled for allergy skin testing, do not take Tricodene SF Liquid for several days before the test because it may decrease your response to the skin tests.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tricodene SF Liquid.


• Use Tricodene SF Liquid with caution in the ELDERLY because they may be more sensitive to its effects.


• Caution is advised when using Tricodene SF Liquid in CHILDREN because they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Tricodene SF Liquid, discuss with your doctor the benefits and risks of using Tricodene SF Liquid during pregnancy. It is unknown if Tricodene SF Liquid is excreted in breast milk. Do not breast-feed while taking Tricodene SF Liquid.

Possible side effects of Tricodene SF Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Tricodene SF side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Tricodene SF Liquid:

Store Tricodene SF Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tricodene SF Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Tricodene SF Liquid, please talk with your doctor, pharmacist, or other health care provider.


• Tricodene SF Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tricodene SF Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tricodene SF resources

• Tricodene SF Side Effects (in more detail)
• Tricodene SF Use in Pregnancy & Breastfeeding
• Tricodene SF Drug Interactions
• Tricodene SF Support Group
• 0 Reviews for Tricodene SF - Add your own review/rating

Compare Tricodene SF with other medications

• Cough and Nasal Congestion

Norethindrone/Ethinyl Estradiol Chewable Tablets

Pronunciation: nor-ETH-in-drone/ETH-i-nil ES-tra-DYE-ol/FER-us FUE-ma-rate
Generic Name: Norethindrone/Ethinyl Estradiol
Brand Name: Femcon Fe

Smoking cigarettes while using Norethindrone/Ethinyl Estradiol Chewable Tablets increases your chance of having heart problems. Do not smoke while using Norethindrone/Ethinyl Estradiol Chewable Tablets. The risk of heart problems increases with age and with frequent smoking. Women older than 35 years old and women who smoke 15 or more cigarettes per day are at a greater risk for heart problems.

Norethindrone/Ethinyl Estradiol Chewable Tablets are used for:

Preventing pregnancy. It may be used for other conditions as determined by your doctor.

Norethindrone/Ethinyl Estradiol Chewable Tablets are a combination progesterone and estrogen birth control pill. It works by preventing ovulation, altering the cervical mucus, and changing the lining of the uterus.

Do NOT use Norethindrone/Ethinyl Estradiol Chewable Tablets if:

• you are allergic to any ingredient in Norethindrone/Ethinyl Estradiol Chewable Tablets


• you are pregnant or think you may be pregnant


• you have a history of blood clotting problems, severe blood clots (eg, in the lungs, legs, eyes), certain blood vessel problems (eg, bleeding in the brain, heart attack, stroke), or breast cancer


• you are at risk for developing severe blood clots or have certain heart problems (eg, certain heart valve problems, certain types of irregular heartbeat)


• you have chest pain caused by angina; certain types of headaches or migraines with aura; severe or uncontrolled high blood pressure; endometrial, cervical, or vaginal cancer; estrogen-dependent growths; undiagnosed abnormal vaginal bleeding; diabetes that affects circulation


• you have liver disease, liver tumors or cancer, or a history of yellowing of the eyes or skin caused by pregnancy or prior birth control use


• you have had surgery and are or will be confined to a bed or a chair for an extended period of time


• you are older than 35 years old and you smoke 15 or more cigarettes per day

Contact your doctor or health care provider right away if any of these apply to you.

Before using Norethindrone/Ethinyl Estradiol Chewable Tablets:

Some medical conditions may interact with Norethindrone/Ethinyl Estradiol Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have endometriosis, growths in the uterus, abnormal mammogram, irregular menstrual periods, or a lump in the breast


• if you have heart problems, diabetes, headaches or migraines, gallbladder problems, high blood cholesterol or lipid levels, high blood pressure, kidney problems, blood problems (eg, porphyria), blood in the urine, depression or other mental/mood problems, lupus, chorea, high blood calcium levels, yellowing of the eyes or skin, pancreas problems (eg, pancreatitis), seizures (eg, epilepsy), or a history of cancer


• if you are overweight, you have not yet had your first menstrual period, or you use tobacco


• if you have given birth or otherwise ended a pregnancy within the past 4 weeks

Some MEDICINES MAY INTERACT with Norethindrone/Ethinyl Estradiol Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Atorvastatin or troleandomycin because they may increase the risk of Norethindrone/Ethinyl Estradiol Chewable Tablets's side effects


• Acitretin, aprepitant, azole antifungals (eg, itraconazole, ketoconazole), barbiturates (eg, phenobarbital), bosentan, carbamazepine, dexamethasone, felbamate, griseofulvin, HIV protease inhibitors (eg, ritonavir), hydantoins (eg, phenytoin), modafinil, nevirapine, oxcarbazepine, penicillins (eg, amoxicillin), phenylbutazone, primidone, rifabutin, rifampin, rufinamide, St. John's wort, tetracyclines (eg, doxycycline), topiramate, or troglitazone because they may decrease Norethindrone/Ethinyl Estradiol Chewable Tablets's effectiveness, resulting in breakthrough bleeding or pregnancy


• Beta-blockers (eg, propranolol), corticosteroids (eg, prednisolone), cyclosporine, or theophylline because the risk of their side effects may be increased by Norethindrone/Ethinyl Estradiol Chewable Tablets


• Clofibric acid, lamotrigine, morphine, salicylic acid, temazepam, or valproic acid because their effectiveness may be decreased by Norethindrone/Ethinyl Estradiol Chewable Tablets


• Penicillamine or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by the ferrous fumarate tablets in Norethindrone/Ethinyl Estradiol Chewable Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Norethindrone/Ethinyl Estradiol Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Norethindrone/Ethinyl Estradiol Chewable Tablets:

Use Norethindrone/Ethinyl Estradiol Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Norethindrone/Ethinyl Estradiol Chewable Tablets. Talk to your pharmacist if you have questions about this information.


• Take Norethindrone/Ethinyl Estradiol Chewable Tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Norethindrone/Ethinyl Estradiol Chewable Tablets may be swallowed whole or chewed and swallowed. If you chew Norethindrone/Ethinyl Estradiol Chewable Tablets, drink a full glass of water (8 oz/240 mL) right after you swallow it.


• If you also take a bisphosphonate (eg, alendronate), do not take Norethindrone/Ethinyl Estradiol Chewable Tablets within 2 hours after you take it.


• If you also take cefdinir, eltrombopag, methyldopa, quinolone antibiotics (eg, levofloxacin), or tetracyclines (eg, doxycycline), you may need to separate them from the ferrous fumarate tablets. Ask your doctor or pharmacist how you should take them with Norethindrone/Ethinyl Estradiol Chewable Tablets.


• Begin taking Norethindrone/Ethinyl Estradiol Chewable Tablets on the first Sunday following the start of your period, unless otherwise directed by your doctor. If your period begins on a Sunday, begin taking Norethindrone/Ethinyl Estradiol Chewable Tablets on that day. Try to take Norethindrone/Ethinyl Estradiol Chewable Tablets at the same time every day, not more than 24 hours apart. After taking the last pill in the pack, start taking the first pill from a new pack the very next day.


• Norethindrone/Ethinyl Estradiol Chewable Tablets may not be effective for up to 7 days after you begin taking the first cycle of pills. Use a back-up method of birth control for the first 7 days after you start Norethindrone/Ethinyl Estradiol Chewable Tablets.


• For Norethindrone/Ethinyl Estradiol Chewable Tablets to be effective it must be taken every day. Do not skip doses.


• If you vomit within 3 to 4 hours after you take Norethindrone/Ethinyl Estradiol Chewable Tablets, follow the instructions for what to do if you miss a pill. If you have diarrhea, use a back-up method of birth control and talk with your doctor.


• If you miss a dose of Norethindrone/Ethinyl Estradiol Chewable Tablets and remember it on the same day, take it as soon as possible and go back to your regular dosing schedule. If you do not remember until the next day or if you miss more than 1 dose of Norethindrone/Ethinyl Estradiol Chewable Tablets, see the additional patient information leaflet that comes with Norethindrone/Ethinyl Estradiol Chewable Tablets or contact your doctor for further instructions. You may need to use an extra form of birth control (eg, condoms). If you are not sure about how to handle missed doses of Norethindrone/Ethinyl Estradiol Chewable Tablets, use an extra form of birth control (eg, condoms) and talk with your doctor.

Ask your health care provider any questions you may have about how to use Norethindrone/Ethinyl Estradiol Chewable Tablets.

Important safety information:

• Norethindrone/Ethinyl Estradiol Chewable Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Norethindrone/Ethinyl Estradiol Chewable Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Follow your doctor's instructions for examining your own breasts, and report any lumps immediately.


• If you will be having surgery or will be confined to a bed or chair for a long period of time (such as a long plane flight), notify your doctor 3 to 4 weeks ahead of time. Special precautions may need to be taken in these circumstances while taking Norethindrone/Ethinyl Estradiol Chewable Tablets.


• You should usually not take Norethindrone/Ethinyl Estradiol Chewable Tablets within 4 weeks after giving birth. or otherwise ending a pregnancy. Discuss any questions or concerns with your doctor.


• Norethindrone/Ethinyl Estradiol Chewable Tablets may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or wear protective clothing when exposed to the sun, sunlamps, or tanning booths.


• Use of Norethindrone/Ethinyl Estradiol Chewable Tablets will not protect against HIV infection or prevent the spread of sexually transmitted diseases (STDs).


• Bleeding or spotting may occur while taking Norethindrone/Ethinyl Estradiol Chewable Tablets. Do not stop taking Norethindrone/Ethinyl Estradiol Chewable Tablets if this occurs. If bleeding or spotting continues for more than 7 days or is heavy, contact your doctor.


• Smoking while using Norethindrone/Ethinyl Estradiol Chewable Tablets may increase your risk of stroke, heart attack, blood clots, high blood pressure, or other diseases of the heart and blood vessels.


• Norethindrone/Ethinyl Estradiol Chewable Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Norethindrone/Ethinyl Estradiol Chewable Tablets.


• Taking certain antibiotics, anticonvulsants, or other medicines, as listed in the interactions section, while you are using Norethindrone/Ethinyl Estradiol Chewable Tablets may decrease the effectiveness of Norethindrone/Ethinyl Estradiol Chewable Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms) until your next period.


• If you wear contact lenses and you develop problems with them, contact your doctor.


• If you miss your period, call your doctor immediately. A missed period may indicate that you are pregnant.


• Norethindrone/Ethinyl Estradiol Chewable Tablets may take time to wear off after your last dose. You may not be able to become pregnant for several months after stopping Norethindrone/Ethinyl Estradiol Chewable Tablets. Discuss any concerns with your doctor or pharmacist.


• Lab tests, such as Pap tests, may be performed while you use Norethindrone/Ethinyl Estradiol Chewable Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Norethindrone/Ethinyl Estradiol Chewable Tablets should not be used in CHILDREN who have not had their first menstrual period; safety and effectiveness in these children have not been confirmed.


• PREGNANCY AND BREAST-FEEDING: Do not use Norethindrone/Ethinyl Estradiol Chewable Tablets if you are pregnant. If you think you may be pregnant, contact your doctor right away. Norethindrone/Ethinyl Estradiol Chewable Tablets are found in breast milk. Do not breast-feed while taking Norethindrone/Ethinyl Estradiol Chewable Tablets.

Possible side effects of Norethindrone/Ethinyl Estradiol Chewable Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Breast tenderness or enlargement; changes in appetite; changes in weight; dizziness; hair loss; headache; nausea; stomach cramps or bloating; unusual spotting or bleeding; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); breast discharge; breast lumps; calf or leg pain, swelling, or tenderness; change in amount of urine produced; change in vaginal secretions; changes in vision or speech; confusion; coughing of blood; crushing chest pain or heaviness in the chest; dark-colored urine; depression; difficulty wearing contact lenses; fainting; fever; fluid retention (swelling of the fingers and ankles); light-colored bowel movements; mental or mood changes; missed menstrual period; numbness of an arm or leg; one-sided weakness; persistent or new headache or migraines; persistent or recurrent abnormal vaginal bleeding; persistent or severe dizziness; severe pain or tenderness in the stomach; shortness of breath; sudden partial or complete loss of vision; sudden severe headache or vomiting; unusual or persistent tiredness, lack of energy, or trouble sleeping; vaginal irritation or discharge; weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include nausea; vaginal bleeding; vomiting.

Proper storage of Norethindrone/Ethinyl Estradiol Chewable Tablets:

Store Norethindrone/Ethinyl Estradiol Chewable Tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Norethindrone/Ethinyl Estradiol Chewable Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Norethindrone/Ethinyl Estradiol Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Norethindrone/Ethinyl Estradiol Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Norethindrone/Ethinyl Estradiol Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Norethindrone/Ethinyl Estradiol resources

• Norethindrone/Ethinyl Estradiol Dosage
• Norethindrone/Ethinyl Estradiol Use in Pregnancy & Breastfeeding
• Norethindrone/Ethinyl Estradiol Drug Interactions
• Norethindrone/Ethinyl Estradiol Support Group
• 654 Reviews for Norethindrone/Ethinyl Estradiol - Add your own review/rating

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Tesamorelin

Pronunciation: TES-a-moe-REL-in
Generic Name: Tesamorelin
Brand Name: Egrifta

Tesamorelin is used for:

Reducing excess stomach fat in certain HIV-infected patients.

Tesamorelin is a human growth hormone-releasing factor (GRF) analog. It works by stimulating the pituitary gland to release growth hormone (GH). This causes the breakdown of excess stomach fat.

Do NOT use Tesamorelin if:

• you are allergic to any ingredient in Tesamorelin or to mannitol


• you are pregnant


• you have cancer, an underactive pituitary gland, or a pituitary gland tumor


• you have had your pituitary gland removed, pituitary gland surgery, radiation treatment of the head, or a head injury

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tesamorelin:

Some medical conditions may interact with Tesamorelin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of cancer, non-cancerous growths, or diabetes


• if you have severe breathing problems (eg, respiratory failure); a serious illness caused by complications from surgery, injury, or trauma; or kidney or liver problems

Some MEDICINES MAY INTERACT with Tesamorelin. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticonvulsants (eg, phenytoin), corticosteroids (eg, prednisone), cyclosporine, or sex hormones (eg, estradiol, testosterone) because the risk of their side effects may be increased by Tesamorelin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tesamorelin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tesamorelin:

Use Tesamorelin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Tesamorelin. Talk to your pharmacist if you have questions about this information.


• Tesamorelin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Tesamorelin at home, a health care provider will teach you how to use it. Be sure you understand how to use Tesamorelin. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• Do not use Tesamorelin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.


• Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into a vein or muscle.


• Be sure to rotate your injection site on the stomach area with each dose as directed. Do not inject Tesamorelin into scar tissue, bruises, or the belly button.


• Do not prepare Tesamorelin until you are ready to use it. After mixing, use Tesamorelin right away and throw away any unused medicine. Do not store prepared doses for later use.


• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.


• If you miss a dose of Tesamorelin, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tesamorelin.

Important safety information:

• The safety of long-term use of Tesamorelin is not known. Contact your doctor if your condition does not improve while you use Tesamorelin.


• Tesamorelin is not intended to manage weight loss.


• Tesamorelin may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.


• Diabetes patients - Tesamorelin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Lab tests, including IGF-I and blood sugar levels, may be performed while you use Tesamorelin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Tesamorelin should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Tesamorelin if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you become pregnant, stop taking Tesamorelin and contact your doctor right away. It is not known if Tesamorelin is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Tesamorelin to the baby.

Possible side effects of Tesamorelin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; night sweats; stomach upset; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; flushing; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); arm, joint, leg, or muscle pain; burning, numbness, or tingling of the skin; decreased sense of touch; fainting or faintness; fast or irregular heartbeat; mental or mood changes (eg, depression); muscle or joint soreness or stiffness; numbness, pain, or weakness in your wrist, hand, or fingers, redness, swelling, itching, pain, irritation, rash, bleeding, or bruising at the injection site; shortness of breath or trouble breathing; swelling of the hands, ankles, or feet; symptoms of high blood sugar (eg, increased thirst, hunger, or urination; confusion; drowsiness; flushing; rapid breathing; fruit-like breath odor).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Tesamorelin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Tesamorelin:

Tesamorelin comes with 2 boxes, one with the medicine and one with syringes, needles, and solution to mix with the medicine. Store the medicine box in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store in original packaging until just before use. Store away from heat, moisture, and light. Do not store in the bathroom. Store the box with the solution, syringes, and needles at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Do not use Tesamorelin after its expiration date. Keep Tesamorelin out of the reach of children and away from pets.

General information:

• If you have any questions about Tesamorelin, please talk with your doctor, pharmacist, or other health care provider.


• Tesamorelin is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tesamorelin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tesamorelin resources

• Tesamorelin Side Effects (in more detail)
• Tesamorelin Use in Pregnancy & Breastfeeding
• Tesamorelin Drug Interactions
• Tesamorelin Support Group
• 2 Reviews for Tesamorelin - Add your own review/rating

• Tesamorelin Professional Patient Advice (Wolters Kluwer)


• tesamorelin Subcutaneous Advanced Consumer (Micromedex) - Includes Dosage Information


• Egrifta Prescribing Information (FDA)


• Egrifta Consumer Overview

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Triamterene

trye-AM-ter-een

Oral route(Capsule)

May cause hyperkalemia, which if uncorrected, is potentially fatal. Hyperkalemia is more likely to occur in patients with renal impairment, diabetes mellitus (with or without recognized renal insufficiency), and in the elderly or severely ill. Monitor serum potassium levels carefully in any patient receiving triamterene .

Commonly used brand name(s)

In the U.S.

• Dyrenium

Available Dosage Forms:

• Tablet


• Capsule

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Diuretic, Potassium Sparing

Uses For triamterene

Triamterene is used alone or in combination with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Triamterene is also used to treat water retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome .

Triamterene is a type of diuretic (water pill) that helps prevent your body from losing too much potassium. It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure .

triamterene is available only with your doctor’s prescription .

Before Using triamterene

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For triamterene, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to triamterene or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of triamterene in the pediatric population. Safety and efficacy have not been established .

Geriatric

No information is available on the relationship of age to the effects of triamterene in geriatric patients .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking triamterene, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using triamterene with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Amiloride


• Eplerenone


• Spironolactone

Using triamterene with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alacepril


• Arginine


• Arsenic Trioxide


• Benazepril


• Captopril


• Cilazapril


• Delapril


• Dofetilide


• Droperidol


• Enalaprilat


• Enalapril Maleate


• Fosinopril


• Imidapril


• Levomethadyl


• Lisinopril


• Methotrexate


• Moexipril


• Pentopril


• Perindopril


• Potassium


• Quinapril


• Ramipril


• Sotalol


• Spirapril


• Tacrolimus


• Temocapril


• Trandolapril


• Zofenopril

Using triamterene with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aceclofenac


• Acemetacin


• Alclofenac


• Amantadine


• Apazone


• Benoxaprofen


• Bromfenac


• Bufexamac


• Carprofen


• Clometacin


• Clonixin


• Dexketoprofen


• Diclofenac


• Diflunisal


• Dipyrone


• Droxicam


• Etodolac


• Etofenamate


• Felbinac


• Fenbufen


• Fenoprofen


• Fentiazac


• Floctafenine


• Flufenamic Acid


• Flurbiprofen


• Gossypol


• Ibuprofen


• Indomethacin


• Indoprofen


• Isoxicam


• Ketoprofen


• Ketorolac


• Licorice


• Lornoxicam


• Meclofenamate


• Mefenamic Acid


• Meloxicam


• Nabumetone


• Naproxen


• Niflumic Acid


• Nimesulide


• Oxaprozin


• Oxyphenbutazone


• Phenylbutazone


• Pirazolac


• Piroxicam


• Pirprofen


• Propyphenazone


• Proquazone


• Sulindac


• Suprofen


• Tenidap


• Tenoxicam


• Tiaprofenic Acid


• Tolmetin


• Zomepirac

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using triamterene with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use triamterene, or give you special instructions about the use of food, alcohol, or tobacco.

• Potassium Containing Food

Other Medical Problems

The presence of other medical problems may affect the use of triamterene. Make sure you tell your doctor if you have any other medical problems, especially:

• Anuria (not able to pass urine) or


• Diabetes or


• Hyperkalemia (high potassium in the blood) or


• Kidney disease, severe or


• Liver disease, severe—Should not be used in patients with these conditions .

• Folic acid deficiency or


• Gout or


• Hyperuricemia (high uric acid in the blood) or


• Hypokalemia (low potassium in the blood) or


• Hyponatremia (low sodium in the blood) or


• Kidney stones, history of—triamterene may make these conditions worse .

Proper Use of triamterene

In addition to the use of triamterene, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet .

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well .

Remember that triamterene will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease .

It is best to take triamterene after a meal .

Dosing

The dose of triamterene will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of triamterene. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (capsules):
  
  • For hypertension or edema:
    
    • Adults—100 milligrams (mg) two times a day. Your doctor may adjust your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of triamterene, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using triamterene

It is very important that your doctor check your progress at regular visits to make sure triamterene is working properly and to decide if you should continue to take it. Blood tests may be needed to check for unwanted effects .

Do not take other medicines unless they have been discussed with your doctor. This especially includes potassium supplements or salt substitutes containing potassium .

triamterene may increase the amount of potassium in your blood. Check with your doctor right away if you are having abdominal pain; confusion; difficulty breathing; irregular heartbeats; nausea or vomiting; nervousness; numbness or tingling in the hands, feet, or lips; shortness of breath; or weakness or heaviness of the legs .

triamterene Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Abdominal or stomach pain


• agitation


• black, tarry stools


• bleeding gums


• blood in the urine or stools


• chills


• clay-colored stools


• cloudy urine


• confusion


• convulsions


• cough


• dark urine


• decreased urine output


• depression


• difficulty breathing


• difficulty swallowing


• dizziness


• dry mouth


• fainting spells


• fast or irregular heartbeats


• fever


• headache


• hives


• hostility


• increased thirst


• irritability


• itching


• joint pain


• lethargy


• loss of appetite


• loss of consciousness


• mood changes


• muscle pain or cramps


• muscle twitching


• nausea or vomiting


• nervousness


• numbness or tingling in the hands, feet, or lips


• pain in the groin or genitals


• pain in the lower back or side


• pinpoint red spots on the skin


• puffiness or swelling of the eyelids or around the eyes, face, lips or tongue


• rapid or unusual weight gain


• seizures


• sharp back pain just below the ribs


• shortness of breath


• skin rash


• stupor


• swelling of the face, ankles, feet, or hands


• tightness in the chest


• unpleasant breath odor


• unusual bleeding or bruising


• unusual tiredness or weakness


• vomiting of blood


• weakness or heaviness of the legs


• wheezing


• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Blurred vision


• diarrhea


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


• indigestion


• pain or weakness in the hands or feet


• passing of gas


• stomach fullness or discomfort


• sweating


• trembling

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Increased sensitivity of skin to sunlight


• redness or other discoloration of the skin


• severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: triamterene side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More triamterene resources

• Triamterene Side Effects (in more detail)
• Triamterene Use in Pregnancy & Breastfeeding
• Triamterene Drug Interactions
• Triamterene Support Group
• 3 Reviews for Triamterene - Add your own review/rating

• triamterene Concise Consumer Information (Cerner Multum)


• Triamterene Professional Patient Advice (Wolters Kluwer)


• Triamterene MedFacts Consumer Leaflet (Wolters Kluwer)


• Triamterene Monograph (AHFS DI)


• Dyrenium Prescribing Information (FDA)

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Tri-Vi-Sol

Pronunciation: VYE-ta-min A/VYE-ta-min D/VYE-ta-min C
Generic Name: Vitamin A/Vitamin D/Vitamin C
Brand Name: Examples include Tri-Vitaminand Tri-Vi-Sol

Tri-Vi-Sol is used for:

Treating vitamin deficiency in infants.

Tri-Vi-Sol is a vitamin combination. It works by providing vitamin A, D, and C to the body.

Do NOT use Tri-Vi-Sol if:

• you are allergic to any ingredient in Tri-Vi-Sol

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tri-Vi-Sol:

Some medical conditions may interact with Tri-Vi-Sol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Tri-Vi-Sol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Acitretin because it may increase the risk of Tri-Vi-Sol's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tri-Vi-Sol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tri-Vi-Sol:

Use Tri-Vi-Sol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tri-Vi-Sol by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Tri-Vi-Sol may be mixed with formula, fruit juice, cereal, or other food.


• Shake well before each use.


• Use the dropper that comes with Tri-Vi-Sol to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Tri-Vi-Sol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tri-Vi-Sol.

Important safety information:

• Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Tri-Vi-Sol should be used with extreme caution in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Tri-Vi-Sol is not approved for use in adults. If you become pregnant while taking Tri-Vi-Sol, contact your doctor. You will need to discuss the benefits and risks of using Tri-Vi-Sol while you are pregnant. It is not known if Tri-Vi-Sol is found in breast milk. If you are or will be breast-feeding while you use Tri-Vi-Sol, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tri-Vi-Sol:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Tri-Vi-Sol. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Tri-Vi-Sol side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Tri-Vi-Sol:

Store Tri-Vi-Sol at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in original packaging until just before use. Store away from heat, moisture, and light. Keep Tri-Vi-Sol out of the reach of children and away from pets.

General information:

• If you have any questions about Tri-Vi-Sol, please talk with your doctor, pharmacist, or other health care provider.


• Tri-Vi-Sol is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tri-Vi-Sol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tri-Vi-Sol resources

• Tri-Vi-Sol Side Effects (in more detail)
• Tri-Vi-Sol Use in Pregnancy & Breastfeeding
• Tri-Vi-Sol Drug Interactions
• Tri-Vi-Sol Support Group
• 0 Reviews for Tri-Vi-Sol - Add your own review/rating

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Norditropin Nordiflex

Pronunciation: SOE-ma-TROE-pin
Generic Name: Somatropin (rDNA origin - Refrigerated)
Brand Name: Examples include Norditropin, Norditropin Nordiflex, and Norditropin FlexPro

Norditropin Nordiflex is used for:

Treating certain children or adults whose bodies do not produce enough growth hormone. It is also used to treat certain children who are not growing normally due to Turner syndrome or Noonan syndrome. It may also be used for other conditions as determined by your doctor.

Norditropin Nordiflex is a growth hormone. It works by stimulating growth in patients who do not make enough natural growth hormone.

Do NOT use Norditropin Nordiflex if:

• you are allergic to any ingredient in Norditropin Nordiflex or to phenol


• you have active or recurring cancer, a brain tumor, or other unusual growths


• you have severe breathing problems (eg, respiratory failure) or serious illness caused by complications from surgery or injury


• you have a certain type of eye problem caused by diabetes (diabetic retinopathy) or if you have had a kidney transplant


• the patient is a child who has Prader-Willi syndrome and is severely overweight or has severe breathing problems (eg, airway blockage, respiratory infection, sleep apnea)


• the patient is a child who has epiphyseal closure (bone growth is complete)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Norditropin Nordiflex:

Some medical conditions may interact with Norditropin Nordiflex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of kidney problems, lung or breathing problems (eg, airway blockage, sleep apnea), an underactive thyroid, heart problems, ear or hearing problems (eg, repeated ear infections), or endocrine problems (eg, pituitary or adrenal gland problems)


• if you have a history of diabetes or high blood sugar levels, or if a member of your family has had diabetes


• if you have a history of leukemia, other types of cancer, or any unusual growths or tumors (especially in the brain)


• if you have curvature of the spine (scoliosis), Prader-Willi syndrome, or a certain eye problem called papilledema (swelling of the area around your optic nerve)


• if you are very overweight or have had recent major surgery or injury

Some MEDICINES MAY INTERACT with Norditropin Nordiflex. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Corticosteroids (eg, prednisone) or estrogens because they may decrease Norditropin Nordiflex's effectiveness


• Anticonvulsants (eg, carbamazepine) or cyclosporine because the risk of their side effects may be increased by Norditropin Nordiflex


• Insulin or other medicines for diabetes because their effectiveness may be decreased by Norditropin Nordiflex

This may not be a complete list of all interactions that may occur. Ask your health care provider if Norditropin Nordiflex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Norditropin Nordiflex:

Use Norditropin Nordiflex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Norditropin Nordiflex. Talk to your pharmacist if you have questions about this information.


• Norditropin Nordiflex is given as an injection under the skin. A health care provider will teach you how to use it. Be sure you understand how to use Norditropin Nordiflex. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• Norditropin Nordiflex should be clear and colorless. Do not use Norditropin Nordiflex if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.


• Be sure to rotate your injection site as directed to help avoid thickening or hardening of the skin.


• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.


• If you miss a dose of Norditropin Nordiflex, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Norditropin Nordiflex.

Important safety information:

• Severe and sometimes fatal lung and breathing problems have occurred with use of Norditropin Nordiflex in certain children with Prader-Willi syndrome. These children were usually either very overweight or had severe breathing problems (eg, airway blockage, sleep apnea, lung or airway infection). The risk may be greater in boys. Children with Prader-Willi syndrome should have certain breathing tests before they start Norditropin Nordiflex. They should be monitored for signs of lung or airway infection. They should also have an effective form of weight control. Contact the doctor at once if the patient develops irregular breathing during sleep, new or increased snoring, or symptoms of lung or airway infection (eg, fever, coughing, sore throat, shortness of breath, chest pain or discomfort).


• Rarely, children using Norditropin Nordiflex have experienced a slipped growth plate in the hip. Contact the doctor right away if the patient develops hip or knee pain or a limp.


• Pancreas inflammation (pancreatitis) has been reported rarely in patients who take Norditropin Nordiflex. The risk may be greater in children, especially in girls who have Turner syndrome. Contact your doctor right away if you develop stomach or back pain.


• Diabetes patients - Norditropin Nordiflex may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Lab tests, including blood sugar levels, thyroid function, and eye exams, may be performed while you use Norditropin Nordiflex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Norditropin Nordiflex with caution in the ELDERLY; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Norditropin Nordiflex while you are pregnant. It is not known if Norditropin Nordiflex is found in breast milk. If you are or will be breast-feeding while you use Norditropin Nordiflex, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Norditropin Nordiflex:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bone pain; headache; increased sweating; mild flu-like symptoms; mild swelling (eg, of the hands or feet); muscle or joint pain; prickling sensation of the skin; redness or itching at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, tingling, itching, or numbness in the palm of the hand, fingers, or wrist; change in appearance or size of a mole; chest pain; confusion; ear pain, discharge, or discomfort; fast heartbeat; fever; hearing problems; hip or knee pain; limp; nausea or vomiting; new growth on the skin; one-sided weakness; persistent or severe cough or sore throat; severe or persistent stomach or back pain; severe or persistent swelling of the hands, ankles, or feet; shortness of breath; slurred speech; snoring or irregular breathing during sleep; sudden, severe, or persistent headache or dizziness; symptoms of high blood sugar (eg, increased thirst, hunger, or urination; unusual weakness); thickened or hardened skin at the injection site; trouble breathing; unusual bruising; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Norditropin Nordiflex side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness; excessive thirst or hunger; fainting; fast heartbeat; frequent urination; swelling of the ankles, feet, or hands.

Proper storage of Norditropin Nordiflex:

Store new (unopened) cartridges and prefilled pens in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Protect from light. Do not use Norditropin Nordiflex past the expiration date on the product label.

For 5 mg per 1.5 mL (orange) and 10 mg per 1.5 mL (blue) strengths: Store used (open) cartridges and prefilled pens in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C), or at room temperature below 77 degrees F (25 degrees C). Do not freeze. Store away from heat, moisture, and light. Throw away any remaining medicine after 4 weeks if stored in the refrigerator or after 3 weeks if stored at room temperature.

For 15 mg per 1.5 mL (green) and 30 mg per 3 mL (purple) strengths: Store used (open) cartridges and prefilled pens in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Throw away any remaining medicine after 4 weeks.

Contact your pharmacist if you have any questions about how to properly store Norditropin Nordiflex. Keep Norditropin Nordiflex out of the reach of children and away from pets.

General information:

• If you have any questions about Norditropin Nordiflex, please talk with your doctor, pharmacist, or other health care provider.


• Norditropin Nordiflex is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Norditropin Nordiflex. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Norditropin Nordiflex resources

• Norditropin Nordiflex Side Effects (in more detail)
• Norditropin Nordiflex Use in Pregnancy & Breastfeeding
• Norditropin Nordiflex Drug Interactions
• Norditropin Nordiflex Support Group
• 0 Reviews for Norditropin Nordiflex - Add your own review/rating

Compare Norditropin Nordiflex with other medications

• Adult Human Growth Hormone Deficiency
• Burns, Nitrogen Retention
• Cachexia
• Hypopituitarism
• Noonan's Syndrome
• Pediatric Growth Hormone Deficiency
• Short Bowel Syndrome
• Short Stature for Age
• Turner's Syndrome